09:00–10:30
Session 2 | Holistic Concepts in GPCR Signal Transduction
Role of GPCRs in regulation of hormone and neurotransmitter release
Heidi Hamm, Nashville (US)
GPCR-mediated endosomal ERK signaling through G proteins: implications to disease
Roger Sunahara, San Diego (US)
New nanobodies illuminate opioid receptor signaling with subcellular precision
Miriam Stoeber, Geneva (CH)
Molecular mechanism for GPCR spatial organization at the cell surface
Gabriele Kockelkoren, Copenhagen (DK)
10:30–11:00
COFFEE BREAK
11:00–12:30
Session 2 | Holistic Concepts in GPCR Signal Transduction
Deciphering structural design principles for interaction specificity in G protein signaling
Mickey Kosloff, Haifa (IL)
Dual-activity GPCR: ACKR3 at the crossroads between chemokine and opioid peptide regulation
Andy Chevigne, Luxembourg (LU)
Lipid regulation of ligand binding to atypical chemokine receptor 3
Martin Gustavsson, Copenhagen (DK)
Unveiling of the elusive signaling pathways activated by the super conserved orphan receptors GPR27, GPR85 and GPR173
Julien Hanson, Liege (BE)
12:30–13:00
Poster Appetizer Session
13:00–14:00
Lunch & Poster Session
14:00–15:30
Session 3 | aGPCR: from Structure to Function
Ligands identification and Structural studies of several aGPCRs
Jin-Peng Sun, Jinan (CN)
GPR133 (ADGRD1) signaling is increased by the dissociation of its extracellular NTF and by binding of its new positive allosteric modulator PTK7
Joshua Frenster, Barcelona (ESP)
Identifying Novel Ligands for ADGRG5/GPR114 with a new Ultra-large Library Screening Algorithm in Rosetta
Jens Meiler, Leipzig (DE)
A transgenic system to monitor adhesion G protein-coupled receptor dissociation
Tobias Langenhan, Leipzig (DE)
15:30–16:15
COFFEE BREAK
16:15–17:15
Session 3 | aGPCR: from Structure to Function
In vivo investigations of adhesion GPCR function
Kelly Monk, Portland (US)
Adhesion GPCRS in oncology: emerging roles, functions and therapeutic directions
David M. Favara, Cambridge (UK)
Regulation of glucose homeostasis by Adhesion GPCRs
Doreen Thor, Leipzig (DE)
19:00–01:00
Gala Dinner at Zoo Leipzig
Entrance: Pfaffendorfer Straße 29, 04105 Leipzig
